| abstract |
FIELD: pharmacology. n SUBSTANCE: application of (R/S)-3-amino-1-[(S)-5-phenyl-[1,2,4] oxadiazol-3-yl)-pyrrolidin-1-yl]-3-(4-fluorophenyl)-propan-1-one (with molecular mass Mr=380) in the form of hydrochloride (in terms of the salt form Mr=380+36.5 (HCl)=416.5), corresponding to the structural formula (I) n as dipeptidyl peptidase-4 inhibitor for treatment of type 2 diabetes mellitus. n EFFECT: chemical structure of the compound prevents its intramolecular cyclization, which preserves chemical and spatial structure in the natural conditions of the human body. n 4 dwg, 1 tbl, 6 ex |