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filingDate 2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2627897-C1
titleOfInvention Method for obtaining of antigen for determination of antibrucellar immunity
abstract FIELD: medicine. n SUBSTANCE: method comprises culturing a brucella culture in a liquid nutrient medium, followed by desired product isolation. Cultivation is carried out at a temperature of 39-40 for 18-24 hours, followed by an increase in temperature to 45-50 within 6-10 hours and an increase in temperature to 60 degrees for 1-2 hours, followed by separation of the bacmass and antigen isolation from the culture medium. n EFFECT: use of this method allows to obtain the brucella antigen, by means of which it is possible to carry out objective monitoring of immunity level induced in animals in response to the introduction of antibrucellar vaccines. n 2 cl, 4 tbl, 36 ex
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