http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2627652-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_658faa6a22515c49b74290e9e65a0bf6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2016-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4f98d2b62c0d5baec551db4a82cf7fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f4af340da16beb46e26175e73d710e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4e927f4fab0eac326fa8b6de0cac65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77767e863d1ba3371f84c2d939faf996 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95fe341c6e4ff05867e7491ebcf19934 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c37c47de18f81fe4afd621d349a511f |
| publicationDate | 2017-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2627652-C1 |
| titleOfInvention | Application of selective immunosorbent for removal of antibodies to type 3 desmoglein from blood serum of patients with vesicular fever |
| abstract | FIELD: medicine. n SUBSTANCE: invention relates to a method for preparation of a selective immunosorbent for removal of antibodies to type 3 desmoglein (Dsg3) from the blood of patients withvesicular fever, including preparation of a Dsg3 solution in a phosphate buffer. Anhydrous NHS-activated agarose is added to the empty centrifuge micro-column, the Dsg3 solution is added to a micro-column with agarose and incubated while mixing; at the end of incubation, the micro-column is centrifuged with cooling, then the resulting filtrate is taken, after which phosphate buffer is added to the column to wash away the unbound Dsg3, centrifuged; the washing procedure is repeated, the filtrates are removed after washing; further, to block the residual active NHS groups of the sorbent, a buffer solution of ethanolamine is added and incubated while mixing; after the incubation is completed, it is centrifuged, the filtrate is removed; the washing procedure is repeated, the filtrates are removed after washing; the ready-made sorbent is used to isolate autoantibodies to Dsg3. n EFFECT: production of selective immunosorbent for selective removal of antibodies to type 3 desmoglein from serum in patients with vesicular fever. n 4 dwg, 1 tbl, 3 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2770444-C1 |
| priorityDate | 2016-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.