http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2626511-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b58f981963f6d55d627139e778c4ef7b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-39 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dc9940f80f34f4f21cd17083048b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87cef56f48aad67eebc5a3893bbb8a76 |
| publicationDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2626511-C2 |
| titleOfInvention | Application of 3-(r)-[3-(2-methoxyphenylthio)-2-(s)-methylpropyl]amino-3,4-dihydro-2h-1,5-benzoxathiepin for treatment of cancer and, particularly, for prevention and/or treatment of cancer metastasis |
| abstract | FIELD: pharmacology. n SUBSTANCE: an application method of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepin or its pharmaceutically acceptable salts for the prevention of cancer metastasis is proposed. Herewith the cancer cells express a voltage-sensitive sodium channel Nav1.5. Also, a pharmaceutical composition for the same purpose and application method of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepin or its pharmaceutically acceptable salts for the prevention of cancer metastasis in patients having one or more cancer cells which express a voltage-sensitive sodium channel Nav1.5, are proposed. n EFFECT: said compound reduces the metastatic current in mammary adenocarcinoma cells and does not interfere with the normal function of the heart even at high doses. n 11 cl, 1 dwg |
| priorityDate | 2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.