| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f0cf94a3a2ec82f5de3ecdf9750b726 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f2e64cea2c1f9b45c58963ac5be3efe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15159554db0ce1a9b9d749395dbe8839
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd9a59ee8d62d7e45a79a5af7a2b8a9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3e015e3371ce989e0f904ede042e632
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cff6b7e6dae7e533bf0c9bbda9370e6 |
| publicationDate |
2017-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2623051-C1 |
| titleOfInvention |
Method for prediction of antiplatelet therapy efficiency reduction risk |
| abstract |
FIELD: medicine. n SUBSTANCE: invention is designed to predict the risk of decrease in the efficiency of antiplatelet therapy with clopidogrel and acetylsalicylic acid preparations (ACA) in patients with ischemic heart disease (IHD) who underwent coronary arteries stenting. DNA is isolated from the venous blood of patients. Polymorphic variants T-786C of the NOS3 gene are determined by allele-specific PCR. Detection of PCR products is performed by electrophoresis method. An increased risk of a decrease in the efficiency of antiplatelet therapy with clopidogrel and acetylsalicylic acid preparations is predicted in carriers of the -786CC genotype of NOS3 gene. n EFFECT: invention allows to assess the risk of developing resistance to antiplatelet drugs and to timely adjust the therapy and improve the quality of treatment. n 2 tbl, 3 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2702753-C1 |
| priorityDate |
2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |