http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2620962-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aee5bcd773958f7940475c4d950eaf54 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 2016-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5436d5266b7dd4aee25c738f864e1a5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_514edc6208112831d891db988035df1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c4cb176f9cc9ca434c8272cd1eab7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79b4b46b1f217eb7d6d1517152527006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11f3ae9a866845af9095652f4cbf3657 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b547f854ed40720ec2698fe8ee9c4816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ae1951fc744aad965efaf10a63fe6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d7a13bdb07acbaf5cf21ba32cf50344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c3792fe63318fd71ae2694e6301b27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72fc25ed3e0bb368addfd077472aceb8 |
| publicationDate | 2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2620962-C1 |
| titleOfInvention | COMPOSITION FOR REPAIRING BONE FABRIC DEFECTS ON THE BASIS OF ADENOVIRAL STRUCTURES, CARRIED BMP-2 cDNA, FIBRIN GEL AND SYNTHETIC β-TRICALCIUMPHOSPHATE AND METHOD OF ITS PRODUCTION |
| abstract | FIELD: biotechnology. n SUBSTANCE: a composition based on recombinant adenovirus of RPAP-BMP-2, fibrin gel and synthetic β-tricalciumphosphate as osteoplastic material is described. A method of producing a composition is proposed comprising the steps of: obtaining pseudo-adenoviral particles carrying the cDNA of bone morphogenetic protein BMP-2; obtaining blood plasma enriched with platelets; producing a composition based on pseudo-adenoviral particles carrying BMP-2 cDNA, platelet gel osteoplastic material, β-tricalciumphosphate. The method provides, firstly, local directional administration of virus particles, and, secondly, allows to delay release of structure after the stage of inflammation, when the migration and differentiation of osteogenic precursors begins, the invention is intended for use in regenerative medicine for the purpose of repairing bone defects, resulting from traumatic and degenerative diseases. n EFFECT: increase in the regenerative capacity of bone tissue. n 5 cl, 2 dwg |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2771961-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020139154-A1 |
| priorityDate | 2016-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.