| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1ac6538cb9917e2d40ebcffc6bbc62a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1003 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f9105900cbce3f19f428b7d27bc3fb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdd488a543be7e4be2e5e43723b904e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0cf2e945a91efaf7449923df741a73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa81ce73c3891a4bd3d4e320e1cd2319
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed0a30a24dc62d00cdb4450334060da0 |
| publicationDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2618886-C2 |
| titleOfInvention |
Non-human animals with modified sequences immunoglobulin heavy chains |
| abstract |
FIELD: biotechnology. n SUBSTANCE: genetically-modified non-human animals with a locus of immunoglobulin light chain containing one or more (but less than for the wild type) variable region gene segments of human immunoglobulin light chain, which may be functionally linked to the nucleotide sequence of the constant region of the light chain. Methods are also provided for obtaining nucleotide sequences that encode the variable domains of immunoglobulin light chains capable of antigen binding in the absence of the heavy chain. n EFFECT: said nucleotide sequence of the rearranged variable region of the human immunoglobulin heavy chain may be functionally linked to the nucleotide sequence of the constant region of the light or heavy chain. n 27 cl, 107 dwg, 8 tbl, 8 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2776821-C2 |
| priorityDate |
2013-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |