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publicationDate 2017-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2615407-C1
titleOfInvention Method for prediction of inotropic therapy resistance for newborns with hypotension by molecular-genetic predictor identification
abstract FIELD: medicine. n SUBSTANCE: invention is intended to predict inotropic therapy resistance for newborns with hypotension. DNA is isolated from peripheral blood samples. Polymerase chain reaction is applied for genotyping of polymorphisms of ADD1:1378G>T, ADRA2A:-1291C>G, SLC6A2:-182T>C, ACE:287bp Ins> Del genes. The likelihood of resistance to treatment is calculated as follows. n EFFECT: invention enables high sensitivity and specificity of inotropic therapy resistance prediction for newborns with hypotension. n 4 tbl, 2 ex
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