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filingDate 2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cee931b6f41d0a4fec68a21af8ba011
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publicationDate 2017-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2614728-C2
titleOfInvention Pharmaceutical composition for oral administration containing statin
abstract FIELD: pharmaceutics. n SUBSTANCE: invention relates to pharmaceutical composition for oral administration containing or consisting of: (i) from 11 to 25 wt% of simvastatin, (ii) from 0.01 to 3 % by weight of first substance (A1) with antioxidant activity, which is butylhydroxyanisole, (iii) from 0.01 to 3 % by weight of second substance (A2) with antioxidant activity, differing from first substance (A1) with antioxidant activity, which is citric acid, and (iv) from 75 to 85 wt% of at least one additive selected from group consisting of filler, binder, agents for controlling fluidity, baking powder and agent preventing adhesion or combinations thereof, where quantitative ratio of butylhydroxyanisole (A1) and citric acid (A2) ranges from 1:95 to 1:30, and wherein above composition is compacted in form of tablet and said tablet has mass from 130 to 300 mg. n EFFECT: invention also relates to use of said pharmaceutical composition in medicine. n 12 cl, 2 ex, 4 tbl, 5 dwg
priorityDate 2011-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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