http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2614119-C9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12218178fd716035fabac9b6f1c2b9c2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 |
| filingDate | 2013-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2848e185565392a3dea2648f9c9639e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad3be0b233f13d65095c608035221ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_467980fd3618c2e2dbef21ab1d21b61e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78fb655c6c9c86439ecf9c851682bf54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1d08d97e9e1110f88daa70641d4e63b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3ffa0a5412995180a36fcdd6ff938d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a16f3fc838f0241be4fd8bbdda1c832f |
| publicationDate | 2017-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2614119-C9 |
| titleOfInvention | Method of producing human immunoglobulin |
| abstract | FIELD: biochemistry. n SUBSTANCE: invention relates to biochemistry. Group of inventions is described, which involves method of producing human immunoglobulin and preparation of human immunoglobulin, obtained using said method. Method includes stage of dissolving of Cohn component I+II+III or Cohn component II+III in water for injections; deposition with caprylic acid or caprylate; first stage of anion-exchange chromatography, involving bringing pH of filtrate obtained at step (2), to 5.2, cleaning by anion-exchange chromatography and obtaining eluating solution; deposition of IgM, including control of conductivity of eluating solution obtained at step (3), up to 500–1,000 µS/cm by means of water and further bringing pH to 6.0–7.3,with subsequent settling for 1–2 hours, filtration and filtrate collection; second stage of anion-exchange chromatography, involving bringing pH of filtrate obtained at step (4) to 5.6, subsequent purification by anion-exchange chromatography and collection of eluating solution; production of human immunoglobulin by dialysis of eluating solution obtained at step (5), by ultrafiltration, obtaining pharmaceutical form and inactivation of viruses. n EFFECT: invention extends range of methods for producing human immunoglobulin. n 9 cl, 2 dwg, 3 tbl, 2 ex |
| priorityDate | 2012-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.