| abstract |
FIELD: biochemistry. n SUBSTANCE: invention relates to biochemistry, namely to monoclonal antibody or its antigen-binding fragment, which specifically binds protein gB of cytomegalovirus (CMV). Invention also discloses nucleic acid coding above antibody, host cell producing above antibody, pharmaceutical composition for treating CMV or induction of resistance to CMV containing said antibody. Invention discloses method of producing above antibody and its antigen-binding fragment, their use for treating CMV or increasing resistance to CMV. n EFFECT: invention is capable of specific binding with CMV, which provides effective treatment of diseases associated with CMV protein expression. n 11 cl, 4 dwg, 2 tbl, 5 ex |