http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2610669-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a0d09c4e78e0f13854eba99d0927d62 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4aaea8e154b17aaf2dbcd9f07830f22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5add4c93fc704239f4652747a2ce637 |
| publicationDate | 2017-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2610669-C1 |
| titleOfInvention | Method for production of proteolytic preparation for medical use |
| abstract | FIELD: medicine, pharmacy. n SUBSTANCE: invention refers to biotechnology. A method for extraction of proteolytic enzymes from the digestive organs of fish is proposed. The method includes tissue homogenizing in a buffer, selection of enzymes in the presence of ammonium sulfate, at that, nucleic acids and lipid-protein complexes are removed from the extract prior to protein precipitation in ammonium sulfate by treatment with a polyethyleneimine solution, added to a final concentration from 0.1 to 0.01 by weight %. Residual pyrogens are separated on a hydrophobic sorbent Sferotsell C-80 with further repeated desalination of the extract. The enzyme solution is sterilized by filtration through a membrane with pore size of 0.2 microns, followed by production of lyophilized formulation of the enzyme preparation. n EFFECT: invention allows to obtain proteolytic enzymes with increased collagenolytic activity. n 6 cl, 1 dwg, 1 tbl, 7 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2777067-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023170064-A1 |
| priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.