abstract |
FIELD: biochemistry. n SUBSTANCE: invention relates to biochemistry, namely to antibody or its fragment, which possess immune responsiveness in relation to protein CAPRIN-1. Invention also discloses antibody, which specifically binds to CAPRIN-1, pharmaceutical composition containing said antibody or its fragment or conjugate for treating or preventing malignant tumors, associated with CAPRIN-1, DNA, coding said antibody. Method of treating or preventing malignant tumors, associated with CAPRIN-1, using disclosed antibody is proposed. n EFFECT: invention enables specific binding to CAPRIN-1, which enables effective treatment of malignant tumor associated with expression of CAPRIN-1. n 8 cl, 8 ex |