http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2610173-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7993f3941238bbeb7b25ce1964fd0eed |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_900faa33b72545e683a8328f6cd659a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86dce30b0e7a3105b40ae89bbe145682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29218c9fe84ac408e12b5e62ea7a834a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_934c8fda1f488a370918048aa30c6f7e |
| publicationDate | 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2610173-C1 |
| titleOfInvention | Recombinant plasmid pfm-ifn-17 providing expression of interferon alpha-2b of human, recombinant plasmid pfm-ap, providing expression of enzyme methionine-aminopeptidase e coli, biplasmid strain escherichia coli fm-ifn-ap (pfm-ifn-17, pfm-ap) - producer (met-) of recombinant interferon alpha -2b of human |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to the biotechnologies. The invention represents the recombinant strain of bacteria E. coli FM-IFN, which is produced by means of the successive transformation of the strain cells E. coli BL21 by recombinant plasmid DNA pFM-AP and pFM-IFN-17, recombinant plasmid DNA pFM-AP with the size of 4,582 b.p., which encodes the inducible synthesis of the enzyme methionine-aminopeptidase E.coli under the control of a lactose promoter and contains the gene cm, which determines the resistances to chloramphenicol, as a genetic marker, recombinant plasmid DNA pFM-IFN-17 with the size of 3,215 b.p., which encodes the synthesis of the interferon alpha-2b of a human under the control the lactose and tryptophanic promotor and terminator of the transcription rrnBT1T2 and contains the synthetic gene km, which determines the resistances to kanamycin, as a genetic marker. n EFFECT: production of recombinant interferon aplpha-2b of a human free from methionine on the N-end with the high output and following the simplified technology. n 4 cl, 8 dwg, 1 tbl, 6 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2697375-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107603937-A |
| priorityDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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