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filingDate 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2609026-C1
titleOfInvention Method for production of 1,1-bis-[n-(peroxymethyl)-n-arylamino]cycloalkanes
abstract FIELD: chemistry. n SUBSTANCE: invention relates to organic chemistry, particularly to production of 1,1-bis[N-(peroxymethyl)-N-arylamino]cycloalkanes of general formula (I), which can be used as preparations having antimalarial activity. Method involves reaction of arylamines (o-toluidine m-, n-chloroaniline, m-, n-fluoroaniline, o-, m-bromoaniline, m-nitroaniline) with formaldehyde and 1,1-dihydroperoxycycloalkanes, where cycloalkane is cyclopentane, cyclohexane, cycloheptane, cyclooctane, in H 2 O at room temperature and atmospheric pressure for 1–3 hours. Output of 1,1-bis[N-(peroxymethyl)-N-arylamino]cycloalkanes is 73–99 %. n EFFECT: novel method for selective production of 1,1-bis[N-(peroxymethyl)-N-arylamino]cycloalkanes of general formula (I). n n n n 1 cl, 1 tbl, 1 ex
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