abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to organic chemistry, specifically to deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)-phenyl]-1,2-dihydroquinoline-3-carboxamide. Invention also relates to a pharmaceutical composition based on deuterium-enriched carboxamide, method for production thereof and method of treating malignant hyperproliferative disorder or autoimmune disease, based on use of deuterium-enriched carboxamide. n EFFECT: technical result is obtaining deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)-phenyl]-1,2-dihydroquinoline-3-carboxamide, having useful biological properties. n 25 cl, 7 dwg, 10 tbl, 1 ex |