http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2607527-C2

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
filingDate 2015-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7b19d780d59b7493e8b00123f136062
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publicationDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2607527-C2
titleOfInvention Covalent monoconjugate of polyethylene glycol with thymosin beta 4, resistant to degradation in bloodstream and method for its production
abstract FIELD: biotechnology. n SUBSTANCE: group of inventions relates to biotechnology and can be used in medicine and pharmaceutical industry. Method for regioselective chemical N-terminal PEGylation of thymosin beta 4. By this method monoconjugate of PEG with thymosin beta 4 is obtained, having improved pharmacokinetic properties. Modification of N-terminal alpha amino group of thymosin beta 4 is confirmed. n EFFECT: use of invention enables to obtain monoPEGylated thymosin beta 4 with high output. n 2 cl, 4 dwg, 3 ex
priorityDate 2015-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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