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filingDate 2011-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7830c13c814b6bf2598ed42b9cf8791b
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publicationDate 2016-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2603103-C2
titleOfInvention Method of producing fibrinogen using strong anion exchange resin and fibrinogen-containing product
abstract FIELD: biotechnology. n SUBSTANCE: group of inventions relates to biotechnology. Invention discloses a method of purifying fibrinogen, a fibrinogen-containing product and use of an anion-exchange resin, containing a hydroxylated methacrylic polymer with trimethylamino groups grafted through binding group, for producing said product using said method. Fibrinogen-containing source undergoes chromatography on anion-exchange resin based on hydroxylated methacrylate polymer with trimethylamino groups grafted through binding group. Fibrinogen-containing product is obtained, having high degree of purity without content of viruses and prions with content of fibronectin of 0.01-1.00 mcg/mg of fibrinogen, fibrinopeptide A 0.01-9.0 ng/mg of fibrinogen, with activity vWF: Ag less than 0.1 IU/mg of fibrinogen, with activity of factor XIII 0.07-1.0 IU/mg of fibrinogen and thrombin activity less than 0.007 IU/mg of fibrinogen. n EFFECT: invention discloses a method of purifying fibrinogen, a fibrinogen-containing product and use of an anion-exchange resin, containing a hydroxylated methacrylic polymer with trimethylamino groups grafted through binding group, for producing said product using said method. n 18 cl, 5 tbl
priorityDate 2010-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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