http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2602664-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e7be1bd6a8c05526783c319d32fb549 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2015-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b317d03e57fa929ffeb5e8ebd5f469d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65e1bbf15e0f44c66f743007403f46b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_679f29a8d9b59c3409ee1f5ceaf9d1bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a94f5a519203a0b806dc304c88ca12e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f576b890e471027fc7eea36169b7ba2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aed949dace1032e99f224dd89de8eb0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af64ae5cab27a471bcfb5bc3797eb959 |
| publicationDate | 2016-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2602664-C1 |
| titleOfInvention | Method of prediction of aspirin resistance |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine, in particular - to cardiology and laboratory diagnostics, and can be used for prediction of aspirin resistance at patients with arterial hypertension associated with a high risk of cardiovascular complications, who is long receiving aspirin in a preventive dose. Method involves selection of blood and carrying out the analysis, from a venous blood allocate DNA, carry out polymerase chain reaction of synthesis of DNA, define a polymorphism of genes T1565S, of gene ITGB3, of platelet fibrinogen receptor and A66G, gene MTRR of methionine synthetase reductase; values of C-reactive protein (CRP), interleukin 33 (IL 33), interleukin 10 (IL 10) are defined by method of a enzyme-linked immunosorbent assay. If the CRP equal or exceeding 0.55 mg/ml, IL 33, equal to or greater than 0.5 pg/mL, and the absence of IL 10 in combination with genotype TC of gene ITGB3 and GG MTRR gene is predicted an aspirin resistance. n EFFECT: technical result consists in increase of reliability of detecting the patients with arterial hypertension for whom chronic ingestion more than 5 months of aspirin in a dose of 0,75 mg is ineffective. n 1 cl, 2 ex |
| priorityDate | 2015-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.