http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2599101-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5709ae4638c4b4e735d0aa58377cb6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2015-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5594fd2e4c3c1bd0873a4baaf68b2728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6152fcc7f2300cde2776d13bbc9e2061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5667dff265c1757d0de81a4772d90e |
| publicationDate | 2016-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2599101-C1 |
| titleOfInvention | Method for differential diagnostic of high-grade differentiated adenocarcinomas and adenomas of colon |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine, namely to pathologic anatomy and oncology, and can be used in early lifetime immunohistochemical diagnostics of high-grade differentiated adenocarcinomas of colon. Method involves that the presence of cells expressing Ki-67 is determined additionally, as well as E-cadherin, p53. If there are cells with hyperexpression of E-cadherin, p53, cyclin D1, Ki-67 proliferation index more than 20 % of cells nuclei, the presence of high-grade differentiated adenocarcinomas with high invasive potential of growth, and in case if there are cells with weak expression of E-cadherin, p53, cyclin D1, Ki-67 proliferation index less than 20 % of cells nuclei, the presence of adenomas with signs of dysplasia of 2-3 degree. n EFFECT: method enables to predict clinical outcome more accurately and to plan therapeutic intervention. n 1 cl, 6 dwg, 1 tbl, 2 ex |
| priorityDate | 2015-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.