| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to derivatives of cis-tetrahydro-spiro(cyclohexane-1,1'-pyrido[3,4-b]indole)-4-amine of formula (III) in form of free bases or physiologically acceptable salts, where R 1 denotes H or CH 3 ; R 2 , R 3 , R 4 and R 5 denotes H or halogen. Invention also relates to a pharmaceutical composition based on compound of formula (III), having activity on ORL1 receptor and ยต-opioid receptor. n EFFECT: obtaining novel compounds having useful biological properties. n 8 cl, 7 tbl, 22 ex |