| abstract |
FIELD: medicine; pharmaceuticals. n SUBSTANCE: disclosed is synthetic hepatoprotective agent of pyrimidine row. Offered application of L-ascorbate of 1-(2-hydroxyethyl)-4,6-dimethyl-1,2-dihydropyrimidin-2-one derivatives of formula I. n EFFECT: compound possesses the ability to reduce functional and structural disorders of hepatocytes and providing faster recovery of structure and function of liver at toxic hepatitis; clinical effectiveness in terms of AlAT and AcAT higher than that of xymedone. n 1 cl, 2 tbl n formula I |