| abstract |
FIELD: biology. n SUBSTANCE: invention relates to microbiology and molecular genetics. Disclosed is a complex of recombinant polypeptides for prevention and treatment of bacterial infections caused by Streptococcus agalactiae and/or Streptococcus pyogenes. Complex comprises in equal portions recombinant polypeptides P6, recScaAB, StV, RV1 and Csp1a having amino acid sequence SEQ ID No: 1-5, respectively. Complex has no toxic action on body in mammals. Causes a synergetic effect during synthesis of specific antibodies anti-P6, anti-recScaAB, anti-StV, anti-PB1 and anti-Csp1a, which have protective action against Streptococcus agalactiae and Streptococcus pyogenes, shows a synergetic effect in relation to Streptococcus agalactiae. n EFFECT: prevention and treatment of bacterial infections caused by Streptococcus agalactiae and/or Streptococcus pyogenes. n 1 cl, 5 tbl, 19 ex, 21 dwg |