abstract |
FIELD: biochemistry. n SUBSTANCE: described is use of antibodies or fragments thereof, which specifically bind hDH4 and block the interaction between Dll4 and Notch receptor for preventing, treating or relieving diabetes mellitus type 1 in an individual. n EFFECT: invention extends range of products for treating, preventing type 1 diabetes mellitus. n 18 cl, 11 dwg, 8 tbl, 6 ex |