http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2586223-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a14ea7650983bcf94ad681f152ae4b50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0602ed2c16ffcc9025094fe67a744e52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c360fc3d458046a38e717bfa946e79ee |
| publicationDate | 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2586223-C2 |
| titleOfInvention | Urea derivatives and therapeutic use thereof in treating, among other things, respiratory tract diseases |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to a compound of formula (I) or its pharmaceutically acceptable salt thereof, wherein R 1 represents radical of formula (IA), (IB), or (IC), wherein R 4b is C 1 -C 6 alkyl, C 3 -C 6 cyclo alkyl, phenyl, which is optionally substituted 1-2 substitutes selected from halogen, hydroxy or O-benzyl; or radical of formula (IIa) or (IIb), wherein n equals 1 or 2; and R 3 and R 4 are independently h or C 1 -C 6 alkyl; R 3b is optionally substituted C 1 -C- 6 alkyl, wherein substitute is selected from (C 1 -C 6 ) alkoxy; y represents-O-; A is a cyclo-alkylene radical, having 5, 6 or 7 atoms of ring condensed with phenyl ring; R 2 represents radical of formula (IIIa), (IIIb), (IIIc), wherein q is equal to 0, 1, 2 or 3; R 7 is -CH 3 ; R 8 is -CH 3 or C 2 H 5 and each presence R 6 is independently H, C 1 -C 6 alkyl. Invention also relates to pharmaceutical composition inhibiting activity of MAP-kinase p38 containing effective amount of compound of formula I, together with one or more pharmaceutically acceptable carriers. n EFFECT: technical result is compound for use in treating disease or condition, which has positive result of MAP-kinase p38 inhibiting. n 11 cl, 2 tbl, 22 ex n (I) n (IA) (IB) (IC) n (IIa) (IIb) n (IIIa) (IIIb) (IIIc) |
| priorityDate | 2010-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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