| abstract |
FIELD: animal breeding. n SUBSTANCE: present invention refers to immuno-stimulating oligodeoxynucleotides of general formula: 5' [G] x {TCG TCG} n TCG[G] z 3' , where x = 3-20, z = 0-10, n = 2-100, and can be used in medicine, particularly in veterinary science. Obtained immuno-stimulating oligodeoxynucleotides or containing them vectors and therapeutic agents can be used for preventing infectious disease in poultry. n EFFECT: present invention enables stimulating activation of NF-kB and IRF3 transcription factors, as well as enhance expression involved in inflammatory process cytokines that promotes formation of active immunity to various infections in poultry. n 9 cl, 10 dwg, 3 ex |