http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2581841-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_154103b025a93f85d644053abdc364fb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-06 |
| filingDate | 2011-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51fa1caac7ab8cd8e24c8098a476d4c6 |
| publicationDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2581841-C2 |
| titleOfInvention | Method for obtaining 2-amino-n-(2,2,2-trifluoroethyl)acetamide |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to methods for obtaining compounds of formula and Method for obtaining formula 1 compounds includes (A) interaction of compound of formula with N,N′-carbonyldiimidazole (binding reagent) in polar aprotic solvent, which does not mix with water, with further addition of salt of formula in presence of base, obtained from binding reagent, with obtaining compound of formula at stage (B) interaction of intermediate compound of formula 4 with hydrogen in presence of hydrogenolysis catalyst is carried out with obtaining formula 1 compound. Method for obtaining salts of formula 1A, wherein X represents Cl, Br, CF 3 CO 2 , CH 3 SO 3 , (SO 4 ) 1/2 or (PO 4 ) 1/3 , includes (A1) interaction of tert-butoxycarbonylglycine with N,N′-carbonyldiimidazole (binding agent) in polar aprotic solvent, which does not mix with water, with further addition of salt of formula 3 in presence of base, obtained from binding reagent, with obtaining compound of formula at stage (B1) interaction of intermediate formula 7 compound with acid HX is performed with obtaining formula 1A compound. n EFFECT: improved methods for obtaining N-(2,2,2-trifluoroethyl)acetamide and its salts, which are used in synthesis of 4-acetyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide. n 14 cl, 16 ex |
| priorityDate | 2010-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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