http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2580835-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a14ea7650983bcf94ad681f152ae4b50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2011-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bf9addf2a106af4ec253a4ebaf96be1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01e04e8be2e52618df8f284199f1bce4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e638656bb44db07e0ac790b4d1be0e87 |
| publicationDate | 2016-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2580835-C2 |
| titleOfInvention | Alkaloid derivatives based on aminoesters and compositions of medications containing them |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to field of organic chemistry, namely to alkaloid derivatives, based on aminoesters of general formula and to their pharmaceutically acceptable salts, wherein R 1 represents phenyl, optionally substituted with one-three substituents, selected from the group, consisting of halogen atoms, COOH; R 2 represents phenyl, optionally substituted with one substituent, selected from the group, consisting of halogen atoms; W is selected from the group, consisting of phenyl, naphthalenyl and heteroaryl (selected from dihydrobenzodioxynyl, dihydrobenzodioxepinyl, dihydrobenzoxazinyl and thiophenyl), with each of phenyl and naphthalenyl is optionally substituted with one or two substituents, similar or different, selected from the group, consisting of halogen atoms, -NO 2 , -CN, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, halogen(C 1 -C 6 )alkyl, halogen(C 1 -C 6 )alkoxy, heterocyclyl (selected from pyrrolidinyl, morpholinyl), phenyl, phenyloxy, halogenphenyl, (C 1 -C 6 )alkyl-NHCO -(C 1 -C 6 )alkyl, -OR 3 , -N(R 3 ) 2 , -SR 3 , -OSO 2 R 3 , -CO 2 R 3 , -OCOR 3 , -CON(R 3 ) 2 , -NHCOR 3 , -NHCO 2 R 3 , -NHSO 2 R 3 , -NHCO-(C 1 -C 6 )alkyl-COOH, -CO 2 -(C 1 -C 6 )alkyl-N (R 3 ) 2 and -CO-morpholinyl; R 3 represents H or is selected from the group, consisting of (C 1 -C 6 )alkyl; A - represents physiologically acceptable anion, selected from Cl - , Br - , TFA - . The invention also relates to application of formula (I) compound. n EFFECT: novel heterocyclic compounds, useful as antagonists of muscarine receptors, have been obtained. n 10 cl, 12 tbl, 39 ex |
| priorityDate | 2010-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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