http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2579511-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_602e183e329d908e2c09f9b9141a6962 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-06 |
| filingDate | 2011-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c98ba1608d03f4bcd16c49d168073d88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_653ec738609a2af317dc1a8515388b49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_071270741d07c45ede28172b38b09ed0 |
| publicationDate | 2016-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2579511-C2 |
| titleOfInvention | Furo[3,2-b]pyran derivatives, applicable in synthesis of analogues |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to compounds of general formulae n , n or , n wherein X represents halogen or oxo; Q represents -C(O)H, -CH=CHC(O)OY 1 , -C(R)H(CH 2 ) n OY 1 or -C(R)HCH 2 C(O)OY 1 ; R represents H; n equals 1 or 2; Y 1 , Y 3 and Y 4 , each independently represents H or protective group for hydroxyl; T represents oxo or -OY 5 ; and Y 5 represents H or protective group for hydroxyl or Y 5 , together with oxygen atom, which it is bound with, represents leaving group, wherein protective group for hydroxyl Y 1 and Y 5 , together with oxygen atom, which each of them is bound with, independently represents C1-C12 alprotective group for hydroxyl, and protective group for hydroxylkyl- or carbocyclic C6-C20 aryl- ester Y 3 and Y 4 , together with oxygen atom, which each of them is bound to, independently represents tri(C1-C6alkyl)silyl or- di(C6-C10aryl)(C1-C6alkyl)silyl- ether protective group for hydroxyl, and leaving group represents (C1-C12)alkylsulphonate or carbocyclic (C6-C20)arylsulphonate, which are used to obtain chalichondrin B analogues for synthesis, such as eribulin and its pharmaceutically acceptable salts. n EFFECT: invention also relates to methods for obtaining ER-804028 and eribulin or its pharmaceutically acceptable salt, for instance eribulin mesilate. n 28 cl, 2 tbl |
| priorityDate | 2010-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.