| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6faff147dad5ddd384801d83b43e0286 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3173ed5f92cd5f82d813c37b5236349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d128528e472c7059436b89a3c410a09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_059fbc0d72a810510643bcd9f3db99f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1eb46b4d14826de20a0015025063edb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cf8d6849f4a17200f9e49b7fad26579
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95cf61112826cc249b75b9d48a4f0e56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d709c0ee8ca19bf42f22aea822a45645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb469caeaee442ff1bb70432d9b8c4ec |
| publicationDate |
2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2577242-C1 |
| titleOfInvention |
Way to create transient retinal ischemia |
| abstract |
FIELD: medicine. n SUBSTANCE: invention can be used to model transient ischemic retina. Modeling is performed by introducing the solution of endothelin-1 (ET-1).into the eye of rat. To do this, perform injection with insulin needle size 0.4×13 mm (27G) at the turn of the cut needle to the upper eyelid to the eye's equator upper-outer quadrant of the conjunctiva. Needle is driven subconjunctivally by at least half of its length in the direction of the posterior pole of the eye. Introduced through the needle is 0, 2 ml of 4·10 -6 M solution of ET-1 in phosphate buffer, pH 7.4. n EFFECT: method provides adequate reproducibility transient ischemia of the retina in the experiment without damaging eye tissue and decreasing the dose of the drug. n 1 cl, 2 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2614937-C1 |
| priorityDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |