http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2577118-C1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_912ada4891f67cdcd6c24be75aa94128
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49
filingDate 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a223b184d34f4c41e051a0c4015b78ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b451d2fdf5dca10dcd1f3a8c59eafba
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publicationDate 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2577118-C1
titleOfInvention Method for determining degree of t-lymphocyte energising
abstract FIELD: medicine. n SUBSTANCE: determining a degree of T-cell energising requires analysing separate patient's peripheral blood lymphocytes by interference microscopy. That involves recovering a sample from patient's blood mononuclear suspension, microscoping in an interference microscope to image a mononuclear in the form of a topogram representing two-dimensional phase thickness distribution reflecting a projection of single cell organelle in the form of optical density areas to calculate considerable parameters; the latter are boundaries of the areas in the phase image of a single cell, which are in accordance with the organelle boundaries, and each of which limits a segment in the phase image of a single cell, a thickness of which is different from that of an adjoining segment or segments, in order to plot characteristic straight lines and an integral function on the basis of a dependence of the segment thicknesses within the areas on a phase volume of the above areas. A degree of T-lymphocyte energising of a single cell is determined by comparing a parameter produced by relating slopes of the characteristic straight lines to the segments of the integral function within a cell reticulum to normal and extreme degrees of cell energising. One of these parameters having a high diagnostic potential may be associated with the reticulum state and mitochondrial refractivity, wherein ATP molecule synthesis, which is a sole and universal energy source for cell processes takes place. n EFFECT: higher information value of the cell images by introducing new parameters. n 12 dwg, 2 tbl
priorityDate 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 20.