http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2568849-C9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3239b97a0f5c8bd63eaa1af034693beb |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 |
| filingDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d19ff316bfe2fd1b23a8e93dafcfffac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d446b749d6ab12537a80da1f1d0c8f90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97edad0f40bfe09bac828fc009a83758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40312f45f44e66a5e2359d0402d6793e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fc2b374ec65fb59c4447cc222c25675 |
| publicationDate | 2016-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2568849-C9 |
| titleOfInvention | Agent representing glycyrrhizic acid amide with 5-aminouracil showing antiviral activity on a/h1n1 influenza virus |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to an agent representing glycyrrhizic acid amide with 5-aminouracil of formula (1) showing antiviral activity on A/H1N1 influenza virus. The presented agent (GA amide (1)) is 5 times less toxic for MDCK cells (CTD 50 300 mcg/ml) than rimantadin, a known antiviral preparation (CTD 50 60 mcg/ml), and possesses high antiviral activity; 50% effective concentration (EC 50 ) of GA amide (1) is 0.2 mcg/ml, and in reference preparations: GA - 174 mcg/ml, rimantadin - 12 mcg/ml. GA amide (1) has a higher selectivity index (SI 1500) as compared to the reference preparations and 500 times as high as that of GA (SI 3.0) and 300 times as much as that of rimantadin (SI 5.0). n EFFECT: higher selectivity index of amide. n 1 tbl, 3 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2791806-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2686743-C1 |
| priorityDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 281.