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filingDate 2011-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7ba61c8443390380deb3de1d8452039
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publicationDate 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2568830-C2
titleOfInvention Non-replicating probiotic microorganisms protecting children from gastrointestinal infections
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: present invention refers to a composition of non-replicating probiotic microorganisms brought into the non-replicating condition by thermal treatment at 120-140°C for 1-120 seconds; the composition is applicable for preventing gastrointestinal infections, particularly diarrhoea in children. n EFFECT: probiotics inactivated by the declared method have shown a decrease of pro-inflammatory/anti-inflammatory cytokines (IL-12/IL-10) ratio in relation to probiotics or living microorganisms subject to 20-min inactivation, ie their anti-inflammatory effect in the composition has appeared to increase. n 10 cl, 11 dwg, 3 ex
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