| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to a pharmaceutical dosed form, which includes the product in the form of a solid dispersion, including N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulphanyl)methyl)propyl)amino)-3-((trifluoromethyl)-sulphonyl)benzosulphonamide or its salt, hydrate or solvate, at least, one pharmaceutically acceptable polymer and, at least, one pharmaceutically acceptable solubiliser. n EFFECT: invention is aimed at the method of manufacturing the pharmaceutical dosed form and application of the dosed form in the treatment of proliferative disorders. n 19 cl, 8 dwg, 6 tbl, 7 ex |