| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_190a37410eb7cfbd860c93ed91fb28ff |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 |
| filingDate |
2014-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f0349e0e21beb27b90eb53dca873d3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c4224890f0f2fffb06d9491f3a7680e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca2219dca00e47a7f93be2de2ac49318
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d59deb5b0610b26f9df355bf7e8a7a54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa11629791c491c5b31ab888c3331d50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71f0814f102ae66b75a4aa55b759d350
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cdfc8ba3254675d576c34f854200c1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2a525b0caf2c46bb069f1f3165cefd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73b32ddc62aaf043f6a169fede6ab1bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79c0336e3b319793d243047ac73f8403 |
| publicationDate |
2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2568365-C1 |
| titleOfInvention |
Method for correction of endothelial dysfunction with combination of rosuvastatin and thioctic acid in hypooestrogen-l-name-induced nictic oxide deficiency |
| abstract |
FIELD: medicine. n SUBSTANCE: method involves simulating a dysfunction by performing a bilateral ovariectomy in Wistar male rats. On the 43rd postoperative days, L-nitro-arginine-methyl ester (L-NAME) is administered intragastrically in a dose of 25 mg/kg daily during 7 days. The induced dysfunction is corrected by daily intragastric administration of Rosuvastatin 0.85 mg/kg and thioctic acid 50 mg/kg during 7 days concurring with the administration of L-NAME into the rats. n EFFECT: method provides activating the correction of the endothelial dysfunction in hypooestrogenemia. n 1 tbl, 1 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2646449-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2624870-C1 |
| priorityDate |
2014-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |