http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2566445-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f38f84a08fb4b22c63d460911988d1c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34 |
| filingDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a560c3d94a97e18591f0b7e2827466eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94e02a33d8e0827d3d661630c5137c2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eee6e6117615f5d3606c9301523f811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f592344a07e51d36c7c783491b8ab40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb193276780793706165a85786593a69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b0bcf3582fd815617dd3dca8b518459 |
| publicationDate | 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2566445-C2 |
| titleOfInvention | 5-oxypyrimidine derivatives possessing immunomodulatory activity |
| abstract | FIELD: chemistry. n SUBSTANCE: invention refers to new 2-isopentyl-4,6-dimethyl-5-oxypyrimidine of formula (I) possessing immunomodulatory activity. The compounds can be used in medicine as an immunomodulatory agent for producing preparations used in treating immunodeficient diseases, infectious diseases, after radiation therapy, in various age-related and functional immune response failures. The compound of formula (I) in stimulating the cell immunity causes the pronounced stimulation of various T-lymphocyte subpopulations when administered in the wide range of doses. (I) , wherein R is isopentyl. A method for producing the compound of formula (I) consists in a reaction of isocapronic acid amide in glacial acetic acid with chloroacetyl acetone to produce 2-isopentyl-4-methyl-5-acetyloxazole, which reacts to ammonia solution to produce a target compound. n EFFECT: compound is low-toxic, has the sufficiently pronounced antioxidant properties having the anti-inflammatory action and improving the body resistance to infections. n 3 cl, 4 tbl, 3 ex |
| priorityDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.