| abstract |
FIELD: medicine. n SUBSTANCE: what is presented is a peptide derivative for producing specific antibodies reacting to isoform 2 of translation elongation factor 1A (eEF1A2), but not reacting to isoform 1 of translation elongation factor 1A (eEF1A1), containing a fragment of the amino acid sequence of eEF1A2 in the position from 330 to 343. There are also presented method for producing the monospecific antibodies reacting to eEF1A2, but not to eEF1A1 on the basis of using the peptide derivative according to the invention, and using it for the affine purification of these monospecific antibodies. n EFFECT: invention can be used for developing immune test systems for identifying cells with changed biological apoptosis control apparatus in biological samples capable of malignant transformation and tumourogenesis. n 3 cl, 9 dwg, 10 ex |