http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2557236-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae10212794160b34478f0d05b6ab6fd7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4035 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-46 |
| filingDate | 2010-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed37ab8af68ac8c4445f5511f57b31a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c27302300c44d228de419adfb833611f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bac8cb7e84f79262010abbb0f5e9ac9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca453ce7bde7a2f086aa95346295511c |
| publicationDate | 2015-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2557236-C2 |
| titleOfInvention | Method of producing 2-(1-phenylethyl)isoindolin-1-one compounds |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to a method of producing a compound of the formula given below or a pharmaceutically acceptable salt thereof. The disclosed method includes a step of reacting a primary amine of formula n or a salt thereof with an ester of 2-(bromomethyl)benzoic acid of formula in the presence of an inorganic base. In said formular, R is C 1 - 8 alkyl; each of R 1 and R 2 is independently an alkyl with 1-4 carbon atoms or an alkoxy group with 1-4 carbon atoms; R 3 is an alkyl with 1-8 carbon atoms; and one or X 1 , X 2 , X 3 and X 4 is independently NHC(O)R 6' , NO 2 or NH 2 , and the others are hydrogen; and R 6' is C 3 -C 8 cycloalkyl. n EFFECT: providing an alternative method of producing 2-(1-phenylethyl)isoindolin-1-one compounds on an industrial scale with high output. n 17 cl, 5 ex |
| priorityDate | 2009-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.