http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2553219-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116e93bb174f86ad75d26ae2d0282b0f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-135 |
filingDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74e9893dbfd437a7b6ba231ebcf92f80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22c578873ab25949e1dbed16b80e55d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d48489c8a8386437ab17625f189bbc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbddb4bcc8f85cc28c2a679b0772a931 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b0a6873b41838679b0f8276677f5b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bdc97fe495a3237754e0d93cf4d26cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42bb12f3c115864f0d1fca16b2f35d31 |
publicationDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2553219-C1 |
titleOfInvention | STRAIN OF FMD VIRUS Aphtae epizooticae OF TYPE A FOR CONTROLLING ANTIGENIC AND IMMUNOGENIC ACTIVITY AND FOR PRODUCTION OF BIOLOGICAL PREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PROPHYLAXIS OF FMD OF TYPE A |
abstract | FIELD: biotechnology. n SUBSTANCE: characterised strain was isolated from diseased pigs and produced by serial passages on sensitive hetero- and homologous cell cultures and deposited in the collection of the FSBI "Federal Animal healthcare centre" under the registration number of FMD virus strain A No.2187/Kuti/2013 (production). The presented strain is reproduced in monolayer cell culture of porcine kidney (PK), passaged cell cultures of kidney of Siberian mountain ibex (SMIK-30), VPK-21 and IB-RS-2. During 18÷24 hours of incubation the virus yield in the said cell cultures reaches the values of 6.0÷7.0 lg TCD 50 /cm 3 . At high multiplicity of infection (1÷10 TCD/cell) causes TCID 50 after 5 hours, while maintaining the original characteristics when passaging in cell cultures for 5 passages. n EFFECT: invention can be used to monitor the antigenic and immunogenic activity and for producing biological products for diagnostics and specific prophylaxis of FMD of type A. n 6 tbl, 6 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2804634-C1 |
priorityDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.