| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to compounds providing the targeted drug delivery to CD1d receptor cells and inducing an immune response as compared to an antigen, to based compositions and to a method using them applicable in medicine, of formula n , n wherein R 1 , R 2 , R 3 , and R 4 represents hydrogen; R 6 represents -(CH 2 ) x CH 3 , x represents an integer from 20 to 25, or -(CH 2 ) x CH=CH(CH 2 ) y CH 3, x, y and z independently represent an integer from 1 to 14, R 5 is described by formula n , n wherein R 8 represents hydrogen, R 7 represents C 3 -C 15 alkyl; X represents N; X represents -(CH 2 ) t , wherein t is an integer within 3-10; Z represents a peptide antigen. n EFFECT: prepared are the new biologically active compounds effective for simulating the immune response. n 12 cl, 6 dwg, 5 ex |