http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2546875-C1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b36f6e570e2c47ebc3234f8cce29a2f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_795ec3a73a31f39577fdb2fe8be68b48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate | 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b851734903950d6a803868108bb53b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e7285584f49eb8e9a34ad4de42a6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d88611375558da265b8cfab5bf616905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1291c0cf0203a4b657edcb27a9b09918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee215b812d66e0b7b3fcb4efe9085eb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c8dd7dfbec0920dfbda7f9913cb4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaaf6a821b58376b808b1190ee7eb682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a55dbcaecb2ed7aae9ff23823380ba18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2b288a96506a768dab30133d68a0aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_915ccef815a861b95d1353a6964a3534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf9d67815dcd51d07b3348543c81f06b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027787d9c2ec607c5710bd30fc3c513a |
publicationDate | 2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2546875-C1 |
titleOfInvention | METHOD FOR OBTAINING IMMUNOGENIC COMPOSITION BASED ON CFP10-DBD HYBRID PROTEIN AND DEXTRANE; pCFP10-DBD RECOMBINANT PLASMIDE; Escherichia coli [pREP4, pCFP10-DBD] STRAIN; CFP10-DBD CHIMERIC PROTEIN AND THEIR APPLICATION |
abstract | FIELD: biotechnologies. n SUBSTANCE: invention represents pCFP10-DBD recombinant plasmide consisting of an artificial bacterial operon of a chimeric protein including a promoter region of early promoter of T5 bacteriophage, a chimeric protein gene consisting of a sequence of protein antigene CFP10 from Mycobacterium tuberculosis, which is merged with a sequence of a dextrane-binding domain (DBD) of dextrane sucrase Leuconostoc citreum KM20, and a transcription terminator, a bacterial operon of beta-lactamase and a bacterial initiation section of replication of ColE1 type. Besides, strain Escherichia coli - a producer of CFP10-DBD chimeric protein is presented. The invention describes a method of immobilisation, concentration and cleaning of the obtained protein on cellulose. The invention describes an immunogenic composition containing CFP10-DBD recombinant protein, which is aimed at induction of immunity against tuberculous infection. n EFFECT: invention enlarges the range of devices used for treatment of tuberculosis. n 4 cl, 6 dwg, 1 tbl, 4 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2724896-C1 |
priorityDate | 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 335.