| abstract |
FIELD: medicine. n SUBSTANCE: claimed group of inventions relates to medicine, namely to therapy and haematology and deals with treatment of increased vascular permeability (vascular leak syndrome). For this purpose effective amount of compound, which has formula: , is introduced. n EFFECT: introduction of claimed compound under control of angiopoetin-2 level provides recovery of vascular wall integrity in case of various diseases, accompanied by increased vascular permeability, due to inhibition of proteintyrosinephosphatase-beta (PTP-β). n 21 cl, 24 ex, 20 tbl, 10 dwg |