http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2538678-C2

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
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filingDate 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23dd725acabaeca698dcaffed76dc02c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1c9a220628088fb25293de34b31a9c7
publicationDate 2015-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2538678-C2
titleOfInvention Method for bioencapsulation
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to bioencapsulation, particularly to a method for cephalosporin bioencapsulation, wherein a microcapsule coating is human leucocyte α- or β-interferon. According to the method, power cephalosporin 0.060 g or 0.075 g respectively and E472c preparation 0.05 g as a surfactant are added to 1% aqueous human leucocyte α- or β-interferon 2 g or 2.5 g; the prepared mixture is stirred until the ingredients of the reaction mixture are dissolved completely. Forming a transparent solution is followed by slow drop-by-drop addition of methyl carbinol 1 ml as a first precipitating agent and isopropanol 5 ml as a second precipitating agent; then acetone is added, and the mixture is dried. The method is implemented at 25°C with no special equipment applied. n EFFECT: simplifying and accelerating the process of microcapsules in interferon and higher weight yield. n 4 ex
priorityDate 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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