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publicationDate 2014-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2535872-C2
titleOfInvention METHOD OF SOLID-PHASE CULTIVATION OF Aspergillus ochraceus TO OBTAIN PROTEINASE - PROTEIN C ACTIVATOR OF BLOOD PLASMA
abstract FIELD: biotechnologies. n SUBSTANCE: method for obtaining proteinase - protein C activator of blood plasma provides for solid-phase cultivation of fungus strain Aspergillus ochraceus BKM F-4104D on a substrate. The substrate contains the following components at a certain ratio: a solid substance or a carrier, glucose, amylum, hydrolysate of fish flour, peptone, NaCl, KH 2 PO 4 , MgSO 4 ยท7H 2 O, and water. As a solid substance or a carrier, vermiculite, polyurethane foam, silica gel or wheat middlings are used. Proteinase activity is up to 300 U/ml. n EFFECT: invention allows obtaining a target product with improved activity. n 5 tbl, 15 ex
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