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filingDate 2011-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc7a4a769c0d1e9988f1fb2e7d325289
publicationDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2535089-C2
titleOfInvention Suspension and hardened composition containing carbostyril derivative and silicone oil and/or silicone oil derivative
abstract FIELD: chemistry. n SUBSTANCE: invention discloses a method of preventing agglomeration of particles of an aripiprazole or 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butox]-1H-quinolin-2-one active ingredient in a suspension containing silicone oil and/or a silicone oil derivative in a dispersion medium, wherein the particle size of the active ingredient is 0.1-200 mcm. The method comprises mixing an active ingredient with silicone oil and/or silicone oil derivative in a dispersion medium such that the silicone oil and/or silicone oil derivative is contained in an amount of 0.001-0.2 pts.wt per 100 pts.wt of the active ingredient contained in the suspension. The invention also relates to a hardened composition for preparing a suspension administered by injection or orally. n EFFECT: preventing agglomeration of active ingredients in a suspension without special treatment. n 9 cl, 4 tbl, 9 ex
priorityDate 2010-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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