http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2533461-C2

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filingDate 2011-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2533461-C2
titleOfInvention Dental preparation free from fluoride ions and anion surfactant possessing high antimicrobial efficiency
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: group of inventions refers to oral care compositions and methods for using them. The presented composition contains 15 to 35 wt % of glycerol; 17 to 45 wt % of propylene glycol; 15 to 35 wt % of sorbitol and less than 10 wt % of water and possesses a relatively high antimicrobial activity, characterized by a load test result calculated as a normalized area under curve (NAUC) making 65-75 or more. The composition is free from anion surfactants and a fluoride ion source. A version of the composition contains glycerol in an amount of 20 to 24 wt %, approximately 25 wt % of propylene glycol, approximately 23 wt % of sorbitol and additionally approximately 0.1 wt % of citric acid. What is also presented is a method of treating or preventing oral diseases involving contacting a patient's oral surface with any of the versions of the above composition. n EFFECT: using the above amounts of glycerol, propylene glycol and sorbitol in a combination with the amount of water limiter to less than 10 wt % enables providing an adequately high level of the antimicrobial activity of the oral care composition in the absence of such ingredients as anion surfactants and a fluoride ion source that in turn enables avoiding side effects caused by these ingredients. n 12 cl, 4 tbl, 3 ex
priorityDate 2010-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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