http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2530496-C1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_502e32d20206c2955793988573af745b |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-51 |
filingDate | 2013-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bf9ffa5b7247a1df18e78115a9f36a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7164a75642cde5434a9fc0178b3e75d |
publicationDate | 2014-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2530496-C1 |
titleOfInvention | Method of producing di(4-cyanophenyl)bromomethane |
abstract | FIELD: chemistry. n SUBSTANCE: method of producing di(4-cyanophenyl)bromomethane can be used as an intermediate product in synthesis of medicinal agents, particularly anticancer drug letrozole. The disclosed method of producing di(4-cyanophenyl)bromomethane includes bromation of di(4-cyanophenyl)methane with bromosuccinimide in an inert solvent in the presence of benzoyl peroxide while heating. The reaction is carried out with an excess of 0.2-0.3 mol bromosuccinimide at 105-115°C. n EFFECT: method increases output and purity of the product. n 2 cl, 2 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113620893-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113620893-A |
priorityDate | 2013-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.