abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to new substituted pyrazino-quinolines of formula: , wherein the values R 1 , R 2 , R 3 , R 4 , R 5 , R 5a , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , X and Y are presented in clause one of the patent claim, and to their pharmaceutically acceptable salts. n EFFECT: compounds can be used for treating cancer. n 14 cl, 24 dwg, 2 tbl, 6 ex |