http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2526263-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68905ed592aec6a6a4984615ec013356 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 |
| filingDate | 2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d41842dd444000a82f642dc2fcd66f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563b370cf7061d0e52a975203b6a9238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e88dd1b690d80e46ce76cb27bf5e906 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e7e314d2fd578ac57750d51ea479850 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53ff264e2e9e9c0e0848724ae5d1754c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24eaa1e954cdcc9b300684bc9d09f33e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3113ad6b702018a3d5a9340b7e6d068b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cbff59119f37ce016e15ff0389af9dd |
| publicationDate | 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2526263-C1 |
| titleOfInvention | Method of obtaining of 2-(1-adamantyl)-5r-tetrazoles, demonstrating activity against type a influenza virus |
| abstract | FIELD: chemistry. n SUBSTANCE: described is an improved method of obtaining 2-(1-adamantyl)-5R-tetrazoles of general formula 1 , where: R=H, CH 3 , C 2 H 5 , or phenyl, possibly substituted with NO 2 or F, consisting in the fact, that a reaction mixture, which consists of carbon acid nitrile (RCN), ammonium azide ( N H 4 + N 3 − n) in a ratio of 1.2-1.8 mol of ammonium azide per 1 mol of nitrile in dimethylformamide, is heated at a temperature of 90-110°C by means of electromagnetic radiation with a frequency of 2450 MHz for not more than 2 hours, with the following processing of obtained 5R-tetrazole with 1-adamantanol in sulphuric acid with the concentration not less than 98 wt %. n EFFECT: method is safe, makes it possible to selectively obtain the target product with the high output due to reduction of a probability of a side process of thermal decomposition of 5R tetrazol and exclusion of a probability of ammonium azide sublimation, the target product is active against the virus of type A. n 1 tbl, 7 ex |
| priorityDate | 2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.