http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2524436-C2

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filingDate 2009-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e74d437b12d07041409659185ce126cc
publicationDate 2014-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2524436-C2
titleOfInvention Method of obtaining liquid fraction, which contains isolated highly molecular capsular polysaccharides of streptococcus pneumoniae, and liquid fraction obtained thereof
abstract FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to the field of biotechnology and deals with a method of obtaining a liquid fraction, which contains isolated highly molecular capsular polysaccharides of Streptococcus pneumoniae. The claimed method includes obtaining a fermentation culture of bacterial cells Streptococcus pneumoniae of serotypes 19A, 6A, 19F or 6B, producing the capsular polysaccharides, which include a phosphodiether bond between the repeated units, introduction of CO 2 into the fermentation culture; lysis of bacterial cells with obtaining the liquid fraction, which contains the said polysaccharides, isolation of the capsular polysaccharides from the cell lysate with obtaining the liquid fraction of the isolated highly molecular capsular polysaccharides with a molecular weight of 480 kDa. n EFFECT: claimed inventions can be used in production of vaccines for immunisation against diseases, caused by Streptococcus pneumoniae. n 14 cl, 3 dwg, 7 tbl, 1 ex
priorityDate 2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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